Learn more about Choline uses, effectiveness, possible side effects, CHOLINE. OTHER NAME(S). Bitartre de Choline, Chlorure de Choline, Choline. Structure, properties, spectra, suppliers and links for: choline chloride, chlorure de choline [French] [INN]. choline chloride [INN]. More CHOLINE. Choline chloride ≥99%; CAS Number: ; EC Number: ; Synonym: (2-Hydroxyethyl)trimethylammonium chloride; Linear Formula: C5H14ClNO;.

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It is bifunctional, containing both quaternary ammonium salt and an alcohol.

Molecular Libraries Screening Center Network. Other names hepacholine, biocolina and lipotril.

Choline chloride – Wikipedia

Trimethyl 2-hydroxy ethyl ammonium chlo ride. Views Read Edit View history. Cboline asthma, mg three times daily has been used See separate listings for Phosphatidylcholine and Lecithin.

It is also used orally for postoperative pain, body building, delaying fatigue in endurance sports, preventing neural tube defects, preventing cancer, Huntington’s chorea, Tourette’s disease, cerebellar ataxia, complex partial seizures, asthma, and as a supplement in infant formulas. Human breast milk contains choline. An average diet supplies mg of choline daily Foods that supply large amounts of choline are liver, muscle meats, fish, nuts, beans, peas, eggs, wheat germ, spinach, and others.

Choline is also readily available in the typical diet However, another observational study shows that higher maternal and cord blood cblorure of choline during the first, second, or third trimester of pregnancy are not associated with improved intelligence in the child at 5 years of age Adding choline to the TPN solution usually improves liver function For children years the AI is mg per day; years, mg per day; years, mg per day ; for infants less than 6 months, mg per day; infants months, mg per day Choline concentrates in nervous tissue Choline is used in cell membrane phospholipids and as a methyl donor for the synthesis of many endogenous compounds.


Journal Publishers via MeSH.

Taking choline orally seems to decrease the severity of symptoms, the number of symptomatic days and the need to use bronchodilators in patients cholind asthma Intravenously, choline has orphan drug status for TPN-associated hepatic steatosis.

Simple Structure Advanced History.

A quaternary ammonium salt with choline cation and chloride anion. Ammonium, 2-hydrox yethyl trimethyl- chloride.

Also, taking choline prior to participating in exhaustive, load-carrying exercise does not improve dexterity, upper or lower body strength, grip strength, or run time-to-exhaustion following exercise compared to placebo However, when only children aged 2. May irritate eyes, skin, chlorurd respiratory tract Alfa Aesar A Some researchers speculate that choline might also have a role in cancer prevention, Also, evidence from two observational studies shows that higher maternal intake of choline during pregnancy is not associated with improved cognitive performance in the child at the age of 3 years or 7 years; however, mean intake of choline in both of these studies was below the recommended adequate intake of mg dailychloure Taking choline orally does not improve chokine in elderly people with memory loss The National Academy of Medicine formerly the Institute of Medicine states that doses chline to 3 grams daily for pregnant and lactating women up to 18 years of age, and 3.

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Choline chloride | – PubChem

High doses can increase the risk of adverse effects Drugs or Compounds in Development. S-adenosylmethionine is the methyl donor for this reaction For details fholine our evidence-based approach, see our Editorial Principles and Process. Dietary intake of choline might also decrease homocysteine levels, a risk factor for cardiovascular disease Taking choline orally does not seem to be effective for delaying fatigue in endurance sports Choline has traditionally been considered a B vitamin.


Average maternal intake of choline in the highest quartile was mg daily, compared to only mg daily in the lowest quartile Publication or Magazine Article.

There is insufficient reliable chopine available about the safety of choline used in higher doses in pregnant or lactating women. Trimethylethanolaminebeta-hydroxyethyl trimethylammonium hydroxide.

Chlorure de choline

Administering choline intravenously is effective for treating total parenteral nutrition-associated hepatic steatosis in patients with choline deficiency, It is a white, water soluble salt used mainly in animal feed.

It is also used for hypercholesterolemia, depression, memory loss, Alzheimer’s disease and dementia, schizophrenia, and fetal alcohol spectrum disorders FASD.

In foodstuffs the compound is often present as phosphatidylcholine. For example, choline can be oxidized to betaine which serves as a methyl donor to convert homocysteine to methionine, then S-adenosylmethionine Preliminary clinical research suggests that taking choline as tricholine citrate mg daily for 8 weeks is less effective than intranasal budesonide mcg twice daily for reducing symptoms of allergic rhinitis A cross-sectional analysis of results from observational and clinical research shows that low dietary intake of choline is associated with increased fibrosis in postmenopausal women with nonalcoholic fatty liver disease but not in children, men, or premenopausal women with this condition.

Warning Alfa Aesar A